ARABIDOPSIS
ACYL-LIPID METABOLISM
  ENZYME & PROTEIN DATA
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Long-Chain Acyl-CoA Synthetase


ATP + Coenzyme A AMP + PPi
long-chain fatty acid
Reaction
acyl-Coenzyme A
Brenda: [6.2.1.3]
IUBMB: [6.2.1.3]
ExPASy: [6.2.1.3]
ExplorEnz: [6.2.1.3]
PDB: [6.2.1.3]

 

Enzyme Pathways

Fatty Acid Synth | Plast FAE & Desat | Prok Gal/Sulpho I | Euk Phospholipid | TAG Degradation | FA Elong & Wax | Cutin I | Suberin I

Locus Data & Links    (May need to scroll right or left to show columns)

Locus Id
(TAIR Link)
Abbrev. Mutant(s)
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Pathway(s) Subcelluar
location
Evidence for
function
Key
References
Comments Microarray
Expression
Proteomics
data
ESTexpression
in other oilseeds
LACS2
Mutant Char.; Heterol Exp'n.
4 Refs
Protein family of 9 members; mutant have defected cuticle; cuticle is more permeable for dyes, interestingly leafs are more resistant to the pathogen Botrytis; LACS2 mutant has defected cuticle
Efp Eth Data
LACS3
Seq. Similarity; Heterol Exp'n.
3 Refs
Efp Eth Data
LACS9
Plastid envelope: proteomics
Heterol Exp'n.; Comple. of yeast mutant
1 Ref
Efp Eth Data
LACS8
Plastid envelope
Heterol Exp'n.; Comple. of yeast mutant
1 Ref
Efp Eth Data
LACS1
Mutant Char.; Heterol Exp'n.; in vitro assays
4 Refs
Has overlapping function with lacs2; mutant shows defects both in wax and cutin monomer synthesis
Efp Eth Data
LACS6
Peroxisome
Mutant Char.
2 Refs
Essential for seedling development
Efp Eth Data
LACS5
Heterol Exp'n.; Comple. of yeast mutant
1 Ref
Efp Eth Data
LACS4
Mutant Char.; Heterol Exp'n.; Comple. of yeast mutant
2 Refs
lacs4 knockout has lower cuticular wax loads especially in combination with lacs1 mutants
Efp Eth Data
LACS7
Peroxisome
Mutant Char.
2 Refs
Essential for early seedling growth
Efp Eth Data