Acyl Lipids: enzymes

ARABIDOPSIS
ACYL-LIPID METABOLISM

ENZYME & PROTEIN DATA

Secondary Alcohol Dehydrogenase


nonacosan-15-ol		nonacosan-15-one

NADH+ H⁺+ O₂

H₂O +NAD⁺

nonacosane

Reaction

nonacosan-15-ol

IUBMB: [1.14.13.*] [1.1.1.-]

Enzyme Pathways

FA Elong & Wax

Locus Data & Links (May need to scroll right or left to show columns)

Locus Id (TAIR Link)	Abbrev.	Mutant(s) (click for pop-up)	Pathway(s)	Subcelluar location	Evidence for function	Key References	Comments	Microarray Expression	Proteomics data	ESTexpression in other oilseeds
At1g57750	CYP96A15 / MAH1	mah1, cyp96a15	FA Elong & Wax	Endomembrane (GFP)	Mutant Char.; in-planta Overexp'n.	2 Refs Greer, S., Wen, M., Bird, D., Wu, X.M., Samuels, L., Kunst, L., and Jetter, R. (2007). The cytochrome p450 enzyme CYP96A15 is the midchain alkane hydroxylase responsible for formation of secondary alcohols and ketones in stem cuticular wax of arabidopsis. Plant Physiol. 145 , 653-667. Wen, M., and Jetter, R. (2009). Composition of secondary alcohols, ketones, alkanediols, and ketols in Arabidopsis thaliana cuticular waxes. J. Exp. Bot. 60 , 1811-1821.	Likely a midchain alkane hydroxylase (MAH1). Proposed to act indirectly as the ketone-forming enzyme by a second hydroxylation on the same carbon, forming an unstable geminal diol, spontaneously forming the ketone. This latter hypothesis remains to be demonstrated.